Both genes were up-regulated in HCC according to the Starbase database [38] (http://starbase.sysu.edu.cn/) (Figure 4A and 4B), and high PTPN1 and MAP3K11 expression was associated with poorer overall survival in the GEPIA database [46] (http://gepia.cancer-pku.cn/) (Figure 4C and 4D). The gene discussed is PTPN1; the disease is hepatocellular carcinoma.