The results showed that SNS-032 inhibited the CTD phosphorylation of RNA Pol II at Ser2, 5 and 7 sites; the expression and phosphorylation at Ser127 of YAP; as well as the expression of apoptosis-related protein survivin in tumor tissues (Fig. 3e), which were consistent with the in vitro findings. This evidence concerns the gene BIRC5 and neoplasm.