AMOTL1 and posterior cortical atrophy: In prostate cancer (PCa), Zhan Yang et al. have shown that an Amotl1-derived circRNA termed circAMOTL1L, is downregulated in PCa and that low expression of circAMOTL1L facilitates PCa cell migration and invasion by downregulating E-cad and upregulating vimentin, which leads to EMT and PCa progression.