Multivariate analysis (stepwise) also showed that BMI and diabetes were associated with IL-18 level (B=0.02, t=2.44, p=0.02; B=0.09, t=2.16, p=0.03, respectively), while smoking, high blood pressure, hyperlipidemia, atrial fibrillation and family history of stroke were not associated with IL-18 level (B=0.07, t=1.19, p=0.24; B=0.01, t=0.26, p=0.80; B=0.03, t=0.60, p=0.55; B=0.05, t=0.51, p=0.61; B=0.04, t=0.54, p=0.59; respectively). This evidence concerns the gene IL18 and atrial fibrillation.