SOST and osteoporosis: This study could not provide background data affecting osteoporosis, such as serum levels of vitamin D and parathyroid hormone (PTH) and diabetes-related risk factors for fractures, such as advanced glycation end-products (AGEs) [25, 26], endogenous secretory receptors for AGEs (esRAGE) [27], and sclerostin [28, 29], on the relationship between TBS and VFs.