SLC22A3 and colorectal carcinoma: The present study explored the influence of organic cation transporter 3 (OCT3) expression on the effects of OXA on CRC cell viability, and investigated the direct effects of OCT3 on viability, invasion and migration of CRC cells using MTT assay, wound healing assay, reverse transcription-quantitative polymerase chain reaction, inductively coupled plasma mass spectrometry and lentiviral interference.