It also affects angiogenesis process in HCC.149, 150 Angiogenesis promoting effects of MVIH were linked to its ability to decrease in PGK1 secretion.149 As a sponge for miR‐199, MVIH orchestrated the suppression of miR‐199 leading to decreased apoptosis and cell proliferation in HCC cells.150 A recent study showed that MVIH controls migration and proliferation of HCC cells by modulating ARID1A‐induced effects on CDKN1A.151 These findings reveal that MVIH possesses the oncogenic potential and it can be exploited to diagnose and predict tumor recurrence in HCC patients. This evidence concerns the gene CDKN1A and hepatocellular carcinoma.