Notably, we demonstrate that SLC1A3 inhibition in combination with ASNase treatment could hinder cancer cell proliferation by inducing either cell cycle arrest or apoptosis, which was observed in ALL cells following ASNase treatment (Kidd, 1953; Broome, 1961; Ueno et al, 1997; Pui et al, 2009). This evidence concerns the gene SLC1A3 and cancer.