The most significant pathway affected was transcriptional misregulation in cancer, which was enriched with up-regulated DEGs, including MEF2C, PROM1, CEBPA, LMO2, FLT3, RUNX1, HMGA2, RUNX2, MEIS1, MYC, and WT1. Some of these genes have been defined as MLL targets genes. This evidence concerns the gene RUNX1 and cancer.