The inhibitors targeting the protein products of BCL2A1 and PLK1 exerted standalone cytotoxicity in all AML cell lines, while the IGF1R inhibitor and the PKC inhibitor exhibited cytotoxicity in 9 and 7 AML cell lines, respectively (Figure 3B, Table 1, and Supplementary Figure 4). Here, PLK1 is linked to acute myeloid leukemia.