ISG20 and cervical squamous cell carcinoma: In order to identify probable master genes among revealed CESC-associated DEGs, we analyzed them in the TCGA database and identified 4 genes (EFNA1, TFRC, HIST1H2BK, ISG20) out of 57 responding to SM treatment, the expression of which was associated with poor clinical outcomes in CESC patients (Figure 7D).