In 27 patients with malignant pulmonary nodules who had only one tumour less than 2 cm, the AUC for platelet ITGA2B was 0.937 (95% CI, 0.865-1.000) with sensitivity of 96.3% and specificity of 81.7%, compared with benign pulmonary nodules patients (Figure 5G, Table 2), was larger than that for CEA (0.640, 0.515-0.765), their combination yielded a rather higher AUC, 0.951 (0.913-0.989) in discriminating SPN. This evidence concerns the gene ITGA2B and neoplasm.