PIK3CA and central nervous system cancer: Among the selected genes, 15 (Araf, Braf, Kras, Ccnd1, Cdk6, Igf1r, Nras, Pik3ca, Pik3r1, Pdgfra, Pdgfrb, Pdgfb, Akt1, Akt2, and Mdm2) were related to glioma and leukemia (Figure 4).