The average tumor volume induced by CHL1-transfected cells was significantly smaller compared to tumors volume induced by non-transfected cells: CHL1-SUNE1 vs Vec-SUNE1 (351.92±70.69mm3 vs 491.56±196.38mm3, P<0.05); CHL1-C666 vs Vec-C666 (93.12±66.41mm3 vs 697.10±207.26mm3, P<0.01). Here, CHL1 is linked to neoplasm.