LDHA and hepatocellular carcinoma: Western blotting analysis of fresh HCC and adjacent non-carcinoma tissues from 14 patients with HCC revealed that NDRG2 decreased while LDHA increased significantly in HCC tissues compared with adjacent non-carcinoma liver tissues (Figure 1B), and thus, there was a negative correlation between the expression of NDRG2 and LDHA in HCC tissues (Figure 1C).