CeRNAs (lncRNAs and circRNAs) have been reported to indirectly modulate mRNAs via regulating overlapping microRNAs, which represents a novel layer of RNA crosstalk and participates in the development and progression of human tumours.24 In our study, we firstly constructed a ceRNA network based on miRNAs-COMMD6 and miRNAs-LncRNAs interactions to analyse the upstream mechanism involved in the regulation of COMMD6 expression. This evidence concerns the gene COMMD6 and neoplasm.