EZH2 and central nervous system cancer: Indeed, we observed significant positive correlations between 13-gene scores and EZH2 levels in glioma (rho = 0.45; P < 0.0001), clear cell renal cell (rho = 0.22; P < 0.0001), papillary renal cell (rho = 0.33; P < 0.0001) and liver (rho = 0.26; P < 0.0001) cancers (Fig. 4a).