SLC39A8 and congenital disorder of glycosylation: This study thus extended the previous reports [17, 47] by discovering yet-another SLC39A8 variant that, when homozygous, causes type II CDG; moreover, this report suggests that deficient ZIP8 in mitochondria can cause a Leigh-like syndrome—perhaps associated with diminished activity of Mn-dependent enzymes such as β-galactosyltransferase and/or mitochondrial manganese-superoxide dismutase (MnSOD) [20].