Another early GWAS discovery of a SLC39A8 variant involved a case-control study of 476 schizophrenia patients and 447 control subjects from Galicia, combined with a replication sample comprising >4000 cases and >15,100 control subjects of European origin; the SNV (rs13107325; p.Ala391Thr) was somewhat significant (P = 2.7 × 10−6) in the collective sample, following Bonferroni correction [60]. This evidence concerns the gene SLC39A8 and schizophrenia.