SLC39A8 and schizophrenia: The brain-gut-microbiome axis—mentioned earlier [78], but beyond the scope of this review—might apply to other inflammation-based disorders, in which the intestine generates a nidus for problems elsewhere in the body; accordingly, SLC39A8, which plays a pivotal role in inflammation [43, 45, 46], is likely linked to disorders such as schizophrenia and OA [vide supra].