By activating the STING pathway, the combination therapy of Olaparib and anti-PD-L1 significantly elevated the abundance of CD3+ T cells and CD8+ cytotoxic T cells in tumor bed while decreased the infiltration of PD-1+/Tim-3+ exhausted T cells and CD25+/FoxP3+ Tregs [110]. The gene discussed is STING1; the disease is neoplasm.