Currently, the treatment for LM consists of using either EGFR-tyrosine kinase inhibitors (TKIs), whole brain radiation therapy (WBRT), Chemotherapy (ChT), intrathecal chemotherapy (ITC), and ventriculoperitoneal-shunt (VP-shunt) [5, 6, 8, 10–12]. The gene discussed is EGFR; the disease is lymphangioma.