APOA1 and type 2 diabetes mellitus: In the control and T2DM group, the levels of lipid showed no significant difference between E3/E3 and ε4 subjects; In the CVD group, E3/E3 patients had higher levels of TC, TG, LDL-C and ApoB than ε4 patients; In CVD patients with T2DM, we found that patients with ε4 allele have higher levels of TG and ApoA1, and lower levels of HDL-C.