Looking specifically at the 10 matched patient sample datasets (eight from Pomerantz + two from our cohort), we found that the AR motif itself was not significantly different between tumor and normal datasets, but FOXA1 (P‐value =< 0.001), HOXB13 (P‐value =< 0.001), and GATA2 (P‐value =< 0.001) motifs were significantly enriched in tumor compared with normal tissue, and conversely, c‐JUN was enriched in normal tissue (P‐value =< 0.001) (Fig. 1C). This evidence concerns the gene HOXB13 and neoplasm.