ALOX5AP and Stroke: Helgadottir et al. [21] from the DeCODE group identified a 4-marker single nuclear polymorphism (SNP) termed Hap A in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene locus that confers a 1.67 greater risk of myocardial infarction and stroke in an Icelandic population.