Eosinophils can exert cytotoxic properties for tumour cell upon activating via the release of several cytotoxic granules, including eosinophil cationic protein (ECP), eosinophil derived neurotoxin (EDN), major basic protein (MBP) and eosinophils peroxidase (EPO). The gene discussed is RNASE3; the disease is neoplasm.