IRS2 and Postural instability: Interestingly, many of the genes (such as sarcoplasmic reticulum Ca2 + -ATPases (SLN), Ras-related glycolysis inhibitor, and calcium channel regulator (Rrad), insulin receptor substrate 2 (irs2), and peptide transporter 2 (PEPT2) (Supplementary Data 1)) are associated with metabolic imbalance and weight-related diseases45,46,47.