WWOX and schizophrenia: For example, Exc-13 records highest number of altered GWAS candidate genes in schizophrenia (Fig. 5e), and many genes like Hs3tst5 (<−4 fold), Kif5c (<−2 fold) or Wwox (>1.5 fold) are regulated in this subtype during adolescence, suggesting a vulnerable neuron subtype in schizophrenia pathogenesis.