As such, and in line with the expression patterns observed in subtypes of human T-ALL (Langenau et al., 2005a), the effect of p53 inactivation during Myc-induced T-ALL onset could be determined by zebrafish studies (Feng et al., 2007, 2010; Gutierrez et al., 2014a). Here, MYC is linked to acute lymphoblastic leukemia.