The first zebrafish models of DBA were established in 2008 by two different laboratories, both using MO injection to knock down rps19. The knockdown led to DBA-like phenotypes hallmarked by defective erythropoiesis and developmental abnormalities (Danilova et al., 2008; Jia et al., 2013; Uechi et al., 2008). The gene discussed is RPS19; the disease is Diamond-Blackfan anemia.