As previously shown [10], the percentages of Vδ2+ and Vδ2+Vγ9+ cells in γδ T cells had significant negative correlations with EDSS scores in untreated MS patients (Vδ2+: r = − 0.366, p = 0.031; and Vδ2+Vγ9+: r = − 0.361, p = 0.033), while such correlations were lost in IFN-β-treated MS patients (Vδ2+: p = 0.053; and Vδ2+Vγ9+: p = 0.068, Fig. 2). This evidence concerns the gene IFNB1 and myeloid sarcoma.