29. Another study indicated a consistence between RhoA expression and the results of a functional study on miR‐126. In particular, miR‐126 downregulated Rho/Rac guanine nucleotide exchange factor 2 and elevated Rho GTPase‐activating protein 5, followed by inactivation of Rho GTPase and the Rho GTPase signaling pathway, to exert its tumor suppressor role in colon cancer cells 43. Here, RHOA is linked to malignant colon neoplasm.