PAK‐1, a serine/threonine kinase, was suggested to play a major role in various cancers.27 Studies have even suggested that PAK‐1 is a tumor oncogene and a therapeutic target for the treatment of cancer.13, 15 Compared to prostate cancer, there are limited studies on the role of PAK‐1 in other cancers. This evidence concerns the gene PAK1 and Familial prostate cancer.