SNHG6 and colorectal carcinoma: SNHG6 knockdown in CRC cells resulted in decreases in p-ULK1, ATG13 and ULK1 proteins which are components of the autophagy initiation complex (Fig. 4a, b); in contrast, the levels of these proteins were upregulated when SNHG6 was overexpressed in CRC cells (Fig. 4c, d).