Among the six genes, 6 methylated sites in ARHGDIB (Fig. 8a–f), 1 methylated site in ARL14 (Fig. 8g), 3 methylated sites in GSTM2 (Fig. 8h–j), 2 methylated sites in LINC00526 (Fig. 8k, l) and 2 methylated sites in LURAP1 (Fig. 8m, n) were significantly associated with BC prognosis. The gene discussed is LINC00526; the disease is breast cancer.