Antibiotics that are effective in treatment of pyogenic liver abscess include third and fourth generation cephalosporins (such as ceftriaxone, cefepime), aminoglycosides, fluoroquinolones, beta-lactam/beta-lactamase inhibitor (piperacillin-tazobactam), carbapenems, and metronidazole.334,345-347 Carbapenems are effective for treatment of liver abscess caused by melioidosis or infection with ESBL producing organism.348,349. Here, LACTB is linked to pyogenic liver abscess.