CD34 and diffuse large B-cell lymphoma: To assess a possible benefit of a normal human immune system for DLBCL growth, we intrahepatically reconstituted newborn mice with CD34+ human HSPCs, allowed the human cells to engraft for 6–8 weeks, and subsequently transplanted the mice subcutaneously or orthotopically with U‐2932 or RC‐K8 cells.