Based on this approach, we selected miR-106b, miR-146b, miR-181a, miR-200a, miR-34a, miR-124b, miR-153, and miR-155 as markers for comparison with the control group and selected the Aβ1–42 monomer, Aβ1–42 oligomer, UCHL1, NLRP3, Tau, STAT3, SORL1, Clusterin, APOE3, APOE4, Nogo-A, IL-13, and Visfatin to serve as AD- and inflammation-related markers. The gene discussed is CLU; the disease is Alzheimer disease.