Thus, CDK1 could be a link between the two signaling pathways, whose coordinated function is necessary for the expression of key mesoderm inducers such as T. FGF has been shown to regulate T expression in Xenopus, zebrafish, chick, and mouse embryos (28, –, 33), and a correlation of FGF signaling and T expression was reported in human cancer cell lines (34). The gene discussed is CDK1; the disease is cancer.