To assess why some PDA cell lines are resistant to CAR T cell killing independent of their tMUC1 expression or the CAR T cell’s ability to express perforin (Figure S1C), or produce IFN-γ and granzyme B (Figure 3 and Figure S1B), we considered some common immune evasion tactics used by tumor cells. The gene discussed is GZMB; the disease is Patent ductus arteriosus.