Furthermore, MUC4 suppression in pancreatic cancer induces a change in the phenotype of cells, reducing the expression of mesenchymal cell-specific markers such as N-cadherin and vimentin and upregulating the expression of epithelial-specific markers such as cytokeratin-18, E-cadherin and occludin [167]. The gene discussed is MUC4; the disease is pancreatic neoplasm.