There was no significant difference regarding BTLA expression on CD4+CD25++CD127− regulatory T-cells of healthy controls (n = 15) as compared to SLE patients (n = 33) (25.8% ± 11.0% vs. 30.5% ± 12.2%, p = 0.20, Figure 2). This evidence concerns the gene CD4 and systemic lupus erythematosus.