GC and type 1 diabetes mellitus: Some studies reported a relationship between genetic polymorphisms of VDBP and T1D [121,122] (as a likely consequence of impaired VDBP affinity for its ligand 1,25-dihydroxyvitamin D and subsequent alteration in 1,25-dihydroxyvitamin D concentrations) [123], even though other studies did not confirm these findings [120,124].