CYP2R1 and type 1 diabetes mellitus: Ramos-Lopez et al. [116] documented an association of single nucleotide polymorphisms (SNPs) in CYP2R1—the gene encoding the vitamin D 25-hydroxylase—in patients with T1D and with their serum 25(OH)D levels, suggesting that the G allele of the rs10741657 SNP is associated with T1D susceptibility, whereas the A allele of the same SNP might confer protection against disease development.