Aspartate-glutamate carrier 1 (AGC1) deficiency is a rare neurological disease caused by mutations in the solute carrier family 25 member 12 (SLC25A12) gene, encoding for the mitochondrial aspartate-glutamate carrier isoform 1 (AGC1) [1,2,3]. The gene discussed is SLC25A12; the disease is nervous system disorder.