The SI was significantly higher in the HLA-B*51:01-positive BD group than that in the HLA-B*51:01-negative BD group when the PBL were stimulated by HSP65, B51PD, and MICA-TM (P < 0.05, P < 0.05, P < 0.05, respectively, Mann–Whitney’s U-test). Here, HLA-B is linked to Behcet disease.