HSPD1 and Behcet disease: Furthermore, several candidate antigens or their peptide motifs [9], such as major histocompatibility complex class I chain-related gene A (MICA) [4], heat shock protein-65 (HSP65) [10], retinal S-antigen [11], and alpha-tropomyosin [12], have been reported to elicit response from PBL of patients with BD.