HLA-B and Behcet disease: Recently, using molecular dynamics simulations, we demonstrated that a 9-mer peptide, MICA-TM, which had been reported to induce proliferation of PBL from patients with BD, had a significantly stronger total binding free energy with the BD-associated HLA alleles (HLA-B*51:01 and A*26:01) than with the non-associated alleles (HLA-B*35:01 and A*11:01) [21].