The ROC curve showed that an ACTH concentration > 28.5 pg/mL was a poor diagnostic test to predict ischemia with an area under the ROC of 0.73, with sensitivity of 66.7% (52.1‐79.2), specificity of 69.1% (58.9‐78.1), and a likelihood ratio of 2.16 for the presence of an ischemic lesion (P < .0001). This evidence concerns the gene POMC and ischemia.