We found that the expression of NONO was suggestively augmented in AAA tissues of ApoE−/− mice compare to the control group (1.14 ± 0.19 vs 1.53 ± 0.23, P < .05, N = 6; Figure 1A,B), indicating that NONO may have involvement in the advancement of AAA. Here, APOE is linked to triple-A syndrome.