While the roles of genes in the RAAS, including angiotensin-converting enzyme (ACE), angiotensinogen (AGT), angiotensin II receptor type 1 (AGTR1), and aldosterone synthase (CYP11B2) genes in hypertension, have been widely studied across different ethnicities [9–11], there have been limited investigations in Thai population. Here, ACE is linked to Hypertension.