Interestingly, while levels of CTIP2 mRNA were not affected along the time course (from 24 h to 96 h of infection), deletion of the Vpr gene (Vpr-deleted virus - ΔVpr) abrogated CTIP2 depletion upon viral expression (Fig. 1B,D, ΔVpr Panels). This evidence concerns the gene BCL11B and infection.