CD274 and neoplasm: To confirm this hypothesis on the role of PD-L1 on tumor cells, we tested also the effects of PD-L1_1 and a commercially available anti-mouse PD-L1 mAb (clone 10F.9G2, BioXcell), previously validated in vivo36, on these pathways in PD-L1-positive colon CT26 tumors in vivo.