In addition, because the WAGR CNV encompasses a large genomic regions that encompass many genes, hampering identification of genetic drivers responsible for specific phenotypes shown in CNVs-associated disease conditions, our data do not exclude the possibility that other genes in 11p13 deletion region, besides BDNF, PAX6, and C11orf46 may have independent effect on axonal and other anatomical phenotypes as well as behavioral outcomes in WAGR syndrome. Here, ARL14EP is linked to WAGR syndrome.