There have been other molecules that participate in Wnt/β-catenin triggered signaling pathway in hepatoblastoma including tumor necrosis factor-α (TNF-α), regenerating islet-derived 1 and 3 α (REG1A and 3A), substance P (SP)/neurokinin-1 receptor and PARP-1. The gene discussed is TAC1; the disease is hepatoblastoma.