ALB and Stroke: Similarly, in the most recent meta-analysis of 83 studies (over two million participants), there was an inverse linear relationship between eGFR and the risk of stroke, with risk of stroke increasing 7% for every 10 mL/min/1.73 m2 decrease in glomerular filtration rate (GFR).7 A 25 mg/mmol increase in the albumin to creatinine ratio (ACR) was associated with a 10% increased risk of stroke.